The human P2RX2 AND P2RX3 genes encode P2X2/P2X3, aheteromeric ionotropic ATP receptor that functions as an ATP-activated cation channel cation channel expressed in CNS and dorsal root ganglion neurons. P2X2/P2X3 receptors expressed in neurons are therapeutic targets in treatment
Creative Biogene [2017-09-18 10:58:27 ]
The human P2RX3 gene encodes P2X3, an ionotropic ATP receptor that functions as an ATP-activated cation channel expressed in spinal cord and sensory neurons. P2X3 receptors are therapeutic targets in treatment of neuropathic and inflammatory pain, inflammatory bowel disease, urin
Creative Biogene [2017-09-18 10:57:46 ]
The human P2RX4 gene encodes P2X4, an ionotropic ATP receptor that functions as an ATP-activated cation channel expressed in the CNS, alveolar macrophages, vascular endothelium, and airway smooth muscle. P2X4 receptors are therapeutic targets in treatment of neuropathic pain, ast
Creative Biogene [2017-09-18 10:57:05 ]
The human P2RX7 gene encodes P2X7, an ionotropic ATP receptor that functions as an ATP-activated cation channel expressed in lymphocytes and microglia. P2X7 receptors are therapeutic targets in treatment of osteoporosis, neuropathic and inflammatory pain, and immune diseases. htt
Creative Biogene [2017-09-18 10:56:23 ]
The human TRPA1 gene encodes the pore-forming subunit of TRPA1, a non-selective cation channel expressed in sensory neurons and hair cells. TRPA1 channels are therapeutic targets in treatment of pain. http://www creative-biogene com/Human-TRPA1-Stable-Cell-Line-CHO-196497-12.html
Creative Biogene [2017-09-18 10:54:54 ]
The human TRPC1 gene encodes the pore-forming subunit of TRPC1, a non-selective, cation-permeable channel expressed in the CNS, vascular endothelium and smooth muscle, lymphocytes and epithelia. TRPC1 channels are therapeutic targets in pulmonary hypertension, vascular inflammati
Creative Biogene [2017-09-18 10:54:09 ]
The human TRPC6 gene encodes the pore-forming subunit of TRPC6, a non-selective, cation-permeable channel. TRPC6 channels are therapeutic targets in asthma, COPD, cancer, and pulmonary hypertension. http://www creative-biogene com/Human-TRPC6-Stable-Cell-Line-HEK293-196500-12.htm
Creative Biogene [2017-09-18 10:53:28 ]
The human TRPM4 gene encodes the pore-forming subunit of TRPM4, a non-selective, cation-permeable channel expressed in lymphocytes, heart, vascular smooth muscle, intestine, and prostate. A gain-of-function mutation in TRPM4 is associated with progressive familial heart block typ
Creative Biogene [2017-09-18 10:52:47 ]
The human TRPM4 gene encodes the pore-forming subunit of TRPM4 (transient receptor potential channel, subtype M4), a monovalent cation-selective channel. http://www creative-biogene com/Human-TRPM4-Stable-Cell-Line-HEK293-196504-12.html
Creative Biogene [2017-09-18 10:51:57 ]
The human TRPM8 gene encodes the pore-forming subunit of TRPM8, a non-selective, cation-permeable channel. TRPM8 channels are therapeutic targets in cancer, overactive bladder, and neuropathic pain. http://www creative-biogene com/Human-TRPM8-Stable-Cell-Line-CHO-196505-12.html
Creative Biogene [2017-09-18 10:50:25 ]
The human TRPV4 gene encodes the pore-forming subunit of TRPV4, a moderately selective (PCa/PNa = 6) cation channel. TRPV4 channels are therapeutic targets in pain and asthma. http://www creative-biogene com/Human-TRPV4-Stable-Cell-Line-CHO-196509-12.html
Creative Biogene [2017-09-18 10:49:21 ]
The human TRPV6 gene encodes the pore-forming subunit of TRPV6, a Ca2+-selective cation channel expressed in kidney and intestine epithelia. http://www creative-biogene com/Human-TRPV6-Stable-Cell-Line-HEK293-196510-12.html
Creative Biogene [2017-09-18 10:48:37 ]
U6-shRNA-GFP AAV (Serotype 6) is the serotype 6 AAV which expresses scramble shRNA under U6 promoter with co-expression of GFP as reporter under CMV promoter. This product used in the gene knockdown experiments as a control in cultured cells and animal experiments. http://www cre
Creative Biogene [2017-09-18 10:37:32 ]
mRFP AAV (Serotype 6) is the serotype 6 AAV which expresses mRFP under the CMV promoter. mRFP AAV (Serotype 6) express a monomeric red fluorescent protein mutant from Discosoma (DsRed), overcome the tetramerization which is toxic to cells. mRFP can be used as a reporter in target
Creative Biogene [2017-08-23 15:57:15 ]
CAG-GFP Adeno-associated virus(AAV Serotype 6) which express eGFP under the control CAG (also known as CBA) promoter which is a combination of the Cytomegalovirus (CMV) early enhancer element and chicken beta-actin promoter for high levels of gene express http://www creative-biog
Creative Biogene [2017-08-23 15:56:31 ]
AAV (Serotype 8) is the serotype 8 AAV with CMV promoter with no insert gene. Used as a control. AAV (Serotype 8),AAV00097Z,AAV (Serotype 8),Premade Adeno-associated virus,Adeno-associated virus,AAV,Stable cell line,transduction http://www creative-biogene com/AAV-Serotype-8-1234
Creative Biogene [2017-08-23 15:54:49 ]
Synapsin-GFP AAV (Serotype 8) is the serotype 8 AAV which express eGFP under the Synapsin promoter which restricts transgene expression only in neurons. http://www creative-biogene com/Synapsin-GFP-AAV-Serotype-8-1234596-86.html
Creative Biogene [2017-08-23 15:52:11 ]
Synapsin-Cre-GFP AAV (Serotype 8) is the serotype 8 AAV which express Cre recombinase and GFP under two separate Synapsin promoters which restricts transgene expression only in neurons. http://www creative-biogene com/Synapsin-Cre-GFP-AAV-Serotype-8-1234597-86.html
Creative Biogene [2017-08-23 15:51:15 ]
mRFP AAV (Serotype 8) is the serotype 8 rAAV which expresses mRFP under the CMV promoter. mRFP AAV (Serotype 8) express a monomeric red fluorescent protein mutant from Discosoma (DsRed), overcome the tetramerization which is toxic to cells. mRFP can be used as a reporter in targe
Creative Biogene [2017-08-23 15:50:32 ]
\"CAG-ChR2-YFP AAV (Serotype 8) is the serotype 8 AAV which express Channelrhodopsin-2 under CAG promoter with YFP tag. Channelrhodopsins are a subfamily of opsin proteins that function as light-gated ion channels and very useful for many bioengineering and neuroscience applicati
Creative Biogene [2017-08-23 15:49:49 ]
