3,5-Di-tert-butylbromobenzene CAS: 22385-77-9 MF: C14H21Br MW: 269.22 mp 62-66 °C(lit.) storage temp. Room temperature. Chemical Properties White solid Purity: 99% Usage: API Package: 1KG foil bag; 25Kg drum Price: us$166.6 ...
Hubei YuanCheng GongChuang Technology Co.Ltd [Chemicals] [Pharmaceutical Chemicals] [2015-06-03 13:50:36 ]
3,4,5-Trimethoxybenzoic acid Name:3,4,5-Trimethoxybenzoic acid CAS :118-41-2 EINECS:204-248-2 Synonyms:Gallic acid trimethyl ether InChI:InChI=1/C10H12O5/c1-13-7-4-6(10(11)12)5-8(14-2)9(7)15-3/h4-5H,1-3H3,(H,11,12) HS Code:29189090 Molecular Formula:C10H12O5 Appearance:white ...
Hubei YuanCheng GongChuang Technology Co.Ltd [Chemicals] [Pharmaceutical Chemicals] [2015-06-03 13:49:57 ]
3,4,5-Trifluorophenol CAS: 99627-05-1 MF: C6H3F3O MW: 148.08 EINECS: 436-160-7 mp 52-55 °C bp 177°C Fp 177°C Chemical Properties white to light yellow crystal powder Usage Intermediates of Liquid Crystals Purity: 99% Usage: API Package: 1KG foil bag; 25Kg drum Price: us$250 ...
Hubei YuanCheng GongChuang Technology Co.Ltd [Chemicals] [Pharmaceutical Chemicals] [2015-06-03 13:48:43 ]
JSH-23 exhibited inhibitory effect with an IC(50) value of 7.1 microM on nuclear factor (NF)-kappaB transcriptional activity in lipopolysaccharide (LPS)-stimulated macrophages RAW 264.7, and interfered LPS-induced nuclear translocation of NF-kappaB without affecting IkappaB ...
Shanghai Sun-shine bio-technology Co., Ltd [Chemicals] [Pharmaceutical Chemicals] [2015-06-03 13:46:33 ]
2,4-Dihydroxybenzoic acid Name:2,4-Dihydroxybenzoic acid Synonym:4-Hydroxysalicylic acid; beta-Resorcylic Acid; BETA RESORCYLIC ACID; β-Resorcylic acid; 2,4-dihydroxybenzoate CAS: 89-86-1 EINECS:201-946-9 Assay:99% M.F:C7H6O4 M.W:154.12 MP:225-227℃ BP:414.8°C at 760 mmHg ...
Hubei YuanCheng GongChuang Technology Co.Ltd [Chemicals] [Pharmaceutical Chemicals] [2015-06-03 13:42:59 ]
DMH-1 is a potent and selective BMP inhibitor with IC50s of 27/107.9/<5 nM for ALK1/2/3 respectively; inactive on ALK5, BMPR2, AMPK and ...
Shanghai Sun-shine bio-technology Co., Ltd [Chemicals] [Pharmaceutical Chemicals] [2015-06-03 13:42:54 ]
Name:2,4-DIFLUOROANILINE Synonym:2,4-DIFLUOROBENZENAMINE 1-AMINO-2,4-DIFLUOROBENZENE 2,4-DIFLUORO-BENZENAMINE 2,4-DIFLUORO-ANILIN ANILINE, 2,4-DIFLUORO- BENZENAMINE, 2,4-DIFLUORO- LABOTEST-BB LTBB000653 AKOS 91127 2,4-DIFLUOROPHENYLAMINE CAS: 367-25-9 76563-56-9 ...
Hubei YuanCheng GongChuang Technology Co.Ltd [Chemicals] [Pharmaceutical Chemicals] [2015-06-03 13:40:52 ]
Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM, with 4- and 6-fold less potency against B-Raf(wt) and c-Raf, respectively. ...
Shanghai Sun-shine bio-technology Co., Ltd [Chemicals] [Pharmaceutical Chemicals] [2015-06-03 13:40:24 ]
6H05 gives the greatest degree of modification, which allosterically modifies the oncogenic G12C mutant of highly homologous protein H-Ras without affecting wild-type K-Ras [1]. 6H05 can be used as an intermediate for the synthesis of other oncogenic K-Ras(G12C) ...
Shanghai Sun-shine bio-technology Co., Ltd [Chemicals] [Pharmaceutical Chemicals] [2015-06-03 13:38:22 ]
2,3-Dichloronitrobenzene Name: 2,3-Dichloronitrobenzene EINECS:221-717-7 Molecular Formula:C6H3Cl2NO2 CAS :3209-22-1 Synonyms:3-Nitro-o-dichlorobenzene; 1,2-dichloro-3-nitro-benzen; 2,3-Dichloro-1-nitrobenzene; 1,2-DICHLORO-3-NITROBENZENE; 2,3-DICHLORONITROBENZENE PESTANAL, 250 ...
Hubei YuanCheng GongChuang Technology Co.Ltd [Chemicals] [Pharmaceutical Chemicals] [2015-06-03 13:37:50 ]
LDN193189(DM 3189) is a selective BMP signaling inhibitor, inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, exhibits 200-fold selectivity for BMP versus TGF-β ...
Shanghai Sun-shine bio-technology Co., Ltd [Chemicals] [Pharmaceutical Chemicals] [2015-06-03 13:34:40 ]
AZ20 decreases pChk1 Ser345, pChk1 Ser317 and pChk1 Ser296 levels in a concentration-dependent manner. Prolonged exposure with AZ20 increases H2AX pan-nuclear staining, indicative of replication ...
Shanghai Sun-shine bio-technology Co., Ltd [Chemicals] [Pharmaceutical Chemicals] [2015-06-03 13:30:46 ]
CZC24832 is a selective inhibitor of PI 3-kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay); exhibits limited off-target effects in kinome profiling of 154 identified lipid and protein kinases and 922 other ...
Shanghai Sun-shine bio-technology Co., Ltd [Chemicals] [Pharmaceutical Chemicals] [2015-06-03 13:27:07 ]
RKI-1447 inhibits potently ROCK1 and ROCK2 in a dose-dependent manner with IC50 values of 14.5 nM and 6.2 nM, respectively. RKI-1447 suppressed phosphorylation of the ROCK substrates MLC-2 and MYPT-1 in human cancer cells, but had no effect on the phosphorylation levels of the ...
Shanghai Sun-shine bio-technology Co., Ltd [Chemicals] [Pharmaceutical Chemicals] [2015-06-03 13:23:13 ]
SGI-1027 is a potent and selective inhibitor of DNA methyltransferase (DNMT) with IC50 of 6, 8, 7.5 μM for DNMT1, DNMT3A, and DNMT3B, respectively. ...
Shanghai Sun-shine bio-technology Co., Ltd [Chemicals] [Pharmaceutical Chemicals] [2015-06-03 13:18:17 ]
UNC2250 is a phosphorylation of endogenous Mer inhibitor with an IC50 of 9.8 nM and blocked ligand-stimulated activation of a chimeric EGFR-Mer protein. ...
Shanghai Sun-shine bio-technology Co., Ltd [Chemicals] [Pharmaceutical Chemicals] [2015-06-03 13:15:28 ]
AHAS inhibitor is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising drug target against Mycobacterium tuberculosis (MTB). ...
Shanghai Sun-shine bio-technology Co., Ltd [Chemicals] [Pharmaceutical Chemicals] [2015-06-03 13:11:21 ]
PF-543 is a novel cell-permeant inhibitor of SphK1 with a Ki of 3.6 nM, PF-543 is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform. ...
Shanghai Sun-shine bio-technology Co., Ltd [Chemicals] [Pharmaceutical Chemicals] [2015-06-03 13:08:40 ]
Alogliptin benzoate(SYR 322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9. ...
Shanghai Sun-shine bio-technology Co., Ltd [Chemicals] [Pharmaceutical Chemicals] [2015-06-03 13:05:15 ]
ML347(DN193719) is a highly selective ALK1/ALK2 inhibitor with IC50s of 46/32 nM; shows >300-fold selectivity for ALK2 vs. ALK3. ...
Shanghai Sun-shine bio-technology Co., Ltd [Chemicals] [Pharmaceutical Chemicals] [2015-06-03 13:02:10 ]
