The enzyme urate oxidase (UO), or uricase or factor-independent urate hydroxylase, absent in humans, catalyzes the oxidation of uric acid to 5-hydroxyisourate: Uric acid + O2 + H2O → 5-hydroxyisourate + H2O2 → allantoin + CO2 ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2016-03-11 15:21:04 ]
The enzyme urate oxidase (UO), or uricase or factor-independent urate hydroxylase, absent in humans, catalyzes the oxidation of uric acid to 5-hydroxyisourate: Uric acid + O2 + H2O → 5-hydroxyisourate + H2O2 → allantoin + CO2 ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2016-03-11 15:20:20 ]
The enzyme urate oxidase (UO), or uricase or factor-independent urate hydroxylase, absent in humans, catalyzes the oxidation of uric acid to 5-hydroxyisourate: Uric acid + O2 + H2O → 5-hydroxyisourate + H2O2 → allantoin + CO2 ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2016-03-11 15:19:37 ]
Sarcosine oxidase (SAO) is an enzyme that catalyzes the oxidative demethylation of sarcosine to yield glycine, H2O2, 5, 10-CH2-tetrahydrofolate in a reaction requiring H4-tetrahydrofolate and oxygen. sarcosine + H2O + O2 = glycine + formaldehyde + ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2016-03-11 15:18:52 ]
In enzymology, a pyruvate oxidase (EC 1.2.3.3) is an enzyme that catalyzes the chemical reaction: pyruvate + phosphate + O2 ↔ acetyl phosphate + CO2 + H2O2. The 3 substrates of this enzyme are pyruvate, phosphate, and O2, whereas its 3 products are acetyl phosphate, CO2, and ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2016-03-11 15:18:15 ]
Phospholipase C is an enzyme with system name phosphatidylcholine cholinephosphohydrolase. This enzyme catalyses the following chemical reaction: a phosphatidylcholine + H2O↔ 1, 2-diacyl-sn-glycerol + phosphocholine. The bacterial enzyme is a zinc protein. It also acts on ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2016-03-11 15:17:38 ]
Malate dehydrogenase is an enzyme in the citric acid cycle that catalyzes the conversion of malate into oxaloacetate (using NAD+) and vice versa (this is a reversible reaction). Malate dehydrogenase is not to be confused with malic enzyme, which catalyzes the conversion of ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2016-03-11 15:16:58 ]
Amine oxidases (AO) are enzymes that catalyze the oxidation of a wide range of biogenic amines including many neurotransmitters, histamine and xenobiotic amines. There are two classes of amine oxidases: flavin-containing (EC 1.4.3.4) and copper-containing (EC 1.4.3.6). ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2016-03-11 15:15:54 ]
In enzymology, a lysophospholipase (EC 3.1.1.5) is an enzyme that catalyzes the chemical reaction: 2-lysophosphatidylcholine + H2O ↔ glycerophosphocholine + a carboxylate. Thus, the two substrates of this enzyme are 2-lysophosphatidylcholine and H2O, whereas its two products ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2016-03-11 15:15:16 ]
In enzymology, a lactate 2-monooxygenase (EC 1.13.12.4) is an enzyme that catalyzes the chemical reaction: (S)-lactate + O2 ↔ acetate + CO2 + H2O. Thus, the two substrates of this enzyme are (S)-lactate and O2, whereas its 3 products are acetate, CO2, and ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2016-03-11 15:14:22 ]
Glutamine synthetase (GS) (EC 6.3.1.2) is an enzyme that plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine: Glutamate + ATP + NH3 → Glutamine + ADP + phosphate. Glutamine Synthetase uses ammonia ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2016-03-11 15:13:21 ]
In enzymology, a glycerol-3-phosphate oxidase (EC 1.1.3.21) is an enzyme that catalyzes the chemical reaction: sn-glycerol 3-phosphate + O2↔ glycerone phosphate + H2O2. Thus, the two substrates of this enzyme are sn-glycerol 3-phosphate and O2, whereas its two products are ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2016-03-11 15:12:38 ]
The activity of glycerol kinase is found widely in nature. In microorganisms GK makes possible the utilization of glycerol as a carbon source. In mammals the enzyme represents a juncture of sugar and fat metabolism; The enzyme is important to the clinical chemist in the ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2016-03-11 15:11:36 ]
Glutamate dehydrogenase (GLDH) is an enzyme, present in most microbes and the mitochondria of eukaryotes, as are some of the other enzymes required for urea synthesis, that converts glutamate to α-ketoglutarate, and vice versa. In animals, the produced ammonia is usually used ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2016-03-11 15:10:44 ]
Glucose-6-phosphate dehydrogenase (G6PD or G6PDH) (EC 1.1.1.49) is an cytosolic enzyme that catalyzes the chemical reaction: D-glucose 6-phosphate + NADP+↔ 6-phospho-D-glucono-1, 5-lactone + NADPH + H+. This enzyme is in the pentose phosphate pathway (see image), a metabolic ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2016-03-11 15:10:00 ]
Glucose-6-phosphate dehydrogenase (G6PD or G6PDH) (EC 1.1.1.49) is an cytosolic enzyme that catalyzes the chemical reaction: D-glucose 6-phosphate + NADP+↔ 6-phospho-D-glucono-1, 5-lactone + NADPH + H+. This enzyme is in the pentose phosphate pathway (see image), a metabolic ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2016-03-11 15:09:19 ]
In enzymology, a NADPH dehydrogenase is an enzyme that catalyzes In enzymology, a NAD (P)H dehydrogenase (quinone) (EC 1.6.5.2) is an enzyme that catalyzes the chemical reaction NAD (P)H + H+ + a quinone↔ NAD (P)+ + a hydroquinone. The 4 substrates of this enzyme are NADH, ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2016-03-11 15:08:39 ]
In enzymology, a choline oxidase (EC 1.1.3.17) is an enzyme that catalyzes the chemical reaction choline + O2↔ betaine aldehyde + H2O2. Thus, the two substrates of this enzyme are choline and O2, whereas its two products are betaine aldehyde and ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2016-03-11 15:07:11 ]
Recombinant Cholesterol Oxidase belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. This enzyme participates in bile acid ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2016-03-11 15:06:24 ]
Recombinant Cholesterol Oxidase belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. This enzyme participates in bile acid ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2016-03-11 15:05:48 ]
