CJC-1295 Acetate

Minimum Order: 1

Packaging: N/A

Delivery: 15 Days

Product Name CJC-1295 Acetate

Sequence Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys(Maleimidopropionyl)-NH2

Cas No. 　863288-34-0

Molecular Formula C165H271N47O46

Molecular Weight 3649.30

Purity (HPLC) 98.0%

Appearance? White powder

Single Impurity(HPLC)? 1.0%

Amino Acid Composition? 10% of theoretical

Peptide Content(N%) 80%(by %N)

Water Content(Karl Fischer)? 6.0%

Acetate Content(HPIC) 15.0%

MS(ESI) 　

Mass Balance? 95.0～105.0%

2. Description:

CJC-1295 is a derivative of human GH-releasing factor1-29(HGRF1-29). HGRF1-29 is a naturally occurring peptide that is actually a truncated form of a larger peptide that binds to the growth hormone secretagogue receptor (GHS-R) and causes the release of growth hormone. CJC-1295 has four amino acids substituted in its chain that result in strong binding to serum albumin and prolong its half-life in the body.

Because of the way CJC-1295 is engineered its half life has been extended from ~7 minutes to greater than 7 days!. This is convenient as it means the product only needs to be injected 1-2 times per week for continuously elevated levels of Human Growth Hormone (HGH) and IGF-1. A single subcutaneous (sc) injection results in measurable quantities of CJC-1295 in the blood for up to 13 days. Additionally, a single dose of 60 ug/kg of CJC-1295 results in elevated levels of growth hormone (125%) while the pulsatile secretion of GH is maintained. Furthermore, 60 ug/kg of CJC-1295 elevated IGF-1 levels to the upper limit of normal. A dose of 30 ug/kg of CJC-1295 given weekly maintained its response with no evidence of desensitization.

The advantage of using CJC-1295 instead of actual HGH injections is that injecting HGH shuts down the body's own natural production and therefore when injections are ceased, the body's ability to produce it's own HGH may be impaired and take some time to recover. Since CJC-1295 only stimulates the body's own HGH production, this risk is not apparent.

Country: China (Mainland)
Business Type: Trading Company,Manufacturer
Market:Americas,European Union,Emerging Markets
Founded Year:2009
Address:No. 496 Zhongshan Road, Wuchang, Wuhan, Hubei, CHINA
Contact:Alan Ma

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CJC-1295 Acetate

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