Aicar
Product Quick Detail
- albert@kafenbio.com
- +8618011892373
- Packaging
- Discreet and Disguised
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Specifications
1.Quick Details:
Acadesine
Alias: AICAR; AICA-RIBOSIDE; AMPK; Z-RIBOSIDE
CAS: 2627-69-2
EINECS: 220-097-5
Molecular Formula: C9H14N4O5
Molecular Weight: 258.23
Assay: 98%
Apperance: White or off-white powder.
Usage: Pharmaceutical intermediates. For the treatment of cardiovascular diseases
2.Product Description:
AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.
- Country: China (Mainland)
- Business Type: Manufacturer
- Market:Americas,Africa,Asia,Emerging Markets,Europe,European Union,G20,Middle East,Oceania,Canada,USA,Brazil,Australia,New Zlealand,UK
- Founded Year:2002
- Address:No.128,Hanxing East Rd,Zhongcun,Panyu District
- Contact:Albert Gordon
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CAS: 2627-69-2 MF: C9H14N4O5 MW: 258.23 EINECS: 220-097-5 Appearance: White powder Purity: 99.8% Solubility: Solu ble in DMSO (15 mg/ml); or water (15 mg/ml). Usage: Gl ucose upta ke stimu lant; AMPK activ ator; AICAR is a nucle oside analo gue that is able to enter nuc leoside ...
Other name: Acadesine,AICAR,AICA-RIBOSIDE,AMPK,Z-RIBOSIDE CAS: 2627-69-2 EINECS: 220-097-5 Molecular Formula: C9H14N4O5 Molecular Weight: 258.23 Assay: 99% Apperance: White or off-white powder. Wuhan Demeikai Biotechnology Co., Ltd is a leading Chemicals manufacture in China, ...
AICAR is a peptide whose technical name is 5-Aminoimidazole-4-carboxamide ribonucleotide. It can also be known as AICA ribonucleotide, ZMP, or Acadesine. It is an intermediate contained in the generation of inosine monophosphate. It primarily functions as an AMP-activated ...
