ACE-031

What is ACE-031?

This is a protein that’s being investigated to determine if it can be used for therapeutic purposes for building muscle and enhancing the strength of test subjects. It does this by allowing molecules to bind to cell surface receptors - this is also where it signals through. These cell surface receptors are known as Activin Receptr Type IIB, also known as ActRIIB. ACE-031 is a recombinant fusion protein that is produced when a portion of the ActRIIB receptor and a part of the standard antibody are joined together. This then creates a decoy version of ActRIIB that circulates and eliminates proteins like GDF-8 (also known as myostatin) and other molecules that limit the muscle’s strength or growth.