Quick Details
ProName: Doxorubicin hydrochloride Cas: 25316-40-9
Molecular Formula: C27H30ClNO11
Appearance: white powder
Application: antineoplastic
Purity: 98.5%
Storage: normal temperature
Related Substances: ≤0.3%
Residue on Ignition: ≤0.1%
Heavy Metal: ≤10ppm
Valid Period: 2year
Function
Doxorubicin hydrochloride is a DNA intercalator and powerful cytotoxic agent. Once it associates with the DNA groove, a covalent linkage forms between a DNA base and the pendant sugar of the small molecule. The intercalation into DNA blocks the replication of DNA by blocking Topo II (Topoisomerase II) This general mechanism gives it efficacy in a wide range of different cell types. Additionally, the expression of the oncogenes c-Myc and c-Jun is also down regulated by the chemical and a significant correlation was reported between the level of expression of these genes and the degree of cell growth inhibition conferred by Doxorubicin. Doxorubicin hydrochloride is an inhibitor of AMPK, TERT and POLR.
Packaging Details
25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside
Delivery Detail: within 3 days when get the payment
Shipping
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