Follistatin-315 1mg/vial

Follistatin-315 1mg/vial

Basic Info

Model NO.: Pharmaceutical Grade/USP

Customized: Non-Customized

Suitable for: Elderly, Adult

Purity: >99%

Mgf Specification: 1mg/Vial

Mgf Fuction: Muscle Mass Gaining

Shipping: FedEx, DHL, EMS, TNT, HK EMS, Eub, Etk

Delivery Time: 4-6 Working Days Door to Door

Export Markets: Global. Especially USA. Brazil, Australia, Canada

Transport Package: Foil Bag

Origin: China

Powder: Yes

Certification: GMP, ISO 9001, USP, BP

State: Solid

Product Name: Follistatin 315

Mgf Appearance: White Lyophilized Powder

Mgf Storage: Store at -20c in Refrigerator

Payment: Western Union, Money Gram, Bannk Transfer, Bitcoin

Reship Policy: Reship for Fee

Specification: 10g

HS Code: 2937290019

Follistatin 315 Description

Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release.

The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA.

Follistatin is a secreted glycoprotein that was first identified as a follicle­stimulating hormone inhibiting substance in ovarian follicular fluid.Human Follistatin cDNA encodes a 344 amino acid protein with a 29 aa signal sequence, an N­terminal atypical TGF binding domain, three Follistatin domains that contain EGF ­like and kazal­like motifs, and a highly acidic C­terminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors..

Applications

Follistatin 315 primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a

particular focus on activin, a paracrine hormone

Either by genetic elimination or by increasing the amount of follistatin, resulted in greatly increased muscle mass.In 2009, research with macaque monkeys demonstrated that regulating follistatin via gene therapy also resulted in muscle growth and increases in strength.A study has also shown that increased levels of follistatin, by leading to increased muscle mass of certain core muscular groups, can increase life expectancy in cases of spinal muscular atrophy in animal models.