New product GW501516
Product Quick Detail
- FOB Price
- USD $20.00 / Piece
- MOQ
- 20
- Place Of Origin
- China
- Packaging
- foil bag
- Delivery
- 7 Days
Specifications
Name: GW501516
CAS No.: 317318-70-0
Appearance: white powder
Purity : 99%
Molecular formula: C21H18F3NO3S2
Molecular weight: 453.50
Detail:
GW501516 also known as GW-501,516, GW1516 and GSK-516.It is a selectiveagonist
GW501516 is a synthetic ligand of PPARδ and belongs to the phenoxyacetic acid derivative. After binding to GW501516, activated PPARδ forms a heterodimer with 9-cis retinoid receptor (RXR) And then identify the peroxisome proliferator response element (PPRE) upstream of the target gene promoter to regulate gene transcription, translation and biological effects downstream of the target gene.
GW501516 inhibits apoptosis of ox-LDL or high glucose-induced HUVECs and attenuates the inhibitory effect of ox-LDL or high glucose on HU-VECs activity.
- Country: China (Mainland)
- Business Type:
- Market:
- Founded Year:2013
- Address:
- Contact:Sara Fu
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