New product GW501516

FOB Price
USD $20.00 / Piece
MOQ
20
Place Of Origin
China
Packaging
foil bag
Delivery
7 Days

Name: GW501516

CAS No.: 317318-70-0

Appearance: white powder

Purity : 99%

Molecular formula: C21H18F3NO3S2

Molecular weight: 453.50

Detail:

GW501516 also known as GW-501,516, GW1516 and GSK-516.It is a selectiveagonist

GW501516 is a synthetic ligand of PPARĪ“ and belongs to the phenoxyacetic acid derivative. After binding to GW501516, activated PPARĪ“ forms a heterodimer with 9-cis retinoid receptor (RXR) And then identify the peroxisome proliferator response element (PPRE) upstream of the target gene promoter to regulate gene transcription, translation and biological effects downstream of the target gene.

GW501516 inhibits apoptosis of ox-LDL or high glucose-induced HUVECs and attenuates the inhibitory effect of ox-LDL or high glucose on HU-VECs activity.

  • Country: China (Mainland)
  • Business Type:
  • Market:
  • Founded Year:2013
  • Address:
  • Contact:Sara Fu
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