The anti-CD3/5T4 antibody targets CD3 and 5T4. The BiTE bispecific antibody can be potentially used for treating colon carcinoma via induction of T cell cytotoxicity.
Targets5T4 & CD3 TypeBiTE Expression HostCHO Species ReactivityHuman Target 15T4 HostHuman Clone5T4-4 scFv (LH) Target 2CD3 HostHuman Purity>95% judged by SDS-PAGE under reducing condition
Applications FC Related DiseaseColon carcinoma Targets Target 15T4 Gene ID7162 UniProt IDQ13641 Alternative NamesTPBG; trophoblast glycoprotein; 5T4; M6P1; 5T4AG; WAIF1; 5T4 oncofetal antigen; 5T4
oncotrophoblast glycoprotein Target 2CD3 Alternative NamesCD3; CD3 T-Cell Co-receptor;CD3D; CD3E; CD3G
http://www.creativebiolabs.net/Bispecific-TPBG-CD3-antibody-35003.htm