Bispecific TPBG/CD3 antibody

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The anti-CD3/5T4 antibody targets CD3 and 5T4. The BiTE bispecific antibody can be potentially used for treating colon carcinoma via induction of T cell cytotoxicity.

Targets5T4 & CD3 TypeBiTE Expression HostCHO Species ReactivityHuman Target 15T4 HostHuman Clone5T4-4 scFv (LH) Target 2CD3 HostHuman Purity>95% judged by SDS-PAGE under reducing condition Applications FC Related DiseaseColon carcinoma Targets Target 15T4 Gene ID7162 UniProt IDQ13641 Alternative NamesTPBG; trophoblast glycoprotein; 5T4; M6P1; 5T4AG; WAIF1; 5T4 oncofetal antigen; 5T4 oncotrophoblast glycoprotein Target 2CD3 Alternative NamesCD3; CD3 T-Cell Co-receptor;CD3D; CD3E; CD3G

http://www.creativebiolabs.net/Bispecific-TPBG-CD3-antibody-35003.htm
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  • Founded Year:2005
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  • Contact:Jerry Carter
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Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Tandem scFv)
Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Tandem scFv)

Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Tandem scFv) is designed to be expressed as a scFv from an anti-CD20 antibody variable domains fused with a scFv from an anti-CD3 antibody variable domains. It contains a His-tag at the C/N terminus for affinity ...

Creative BioLabs

Bispecific TPBG/CD3 antibody
Bispecific TPBG/CD3 antibody

http://www.creativebiolabs.net/Bispecific-TPBG-CD3-antibody-35001.htm In immunology, the CD3 (cluster of differentiation 3) T-cell co-receptor is a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two ...

Creative Biolabs