Collagen is the main structural protein in the extracellular space in the various connective tissues in animal bodies. As the main component of connective tissue, it is the most abundant protein in mammals, making up from 25% to 35% of the whole-body protein content. Collagen consists of amino acids wound together to form triple-helices to form of elongated fibrils. It is mostly found in fibrous tissues such as tendons, ligaments and skin.
Depending upon the degree of mineralization, collagen tissues may be rigid (bone), compliant (tendon), or have a gradient from rigid to compliant (cartilage). It is also abundant in corneas, cartilage, bones, blood vessels, the gut, intervertebral discs, and the dentin in teeth. In muscle tissue, it serves as a major component of the endomysium. Collagen constitutes one to two percent of muscle tissue, and accounts for 6% of the weight of strong, tendinous muscles. The fibroblast is the most common cell that creates collagen. Gelatin, which is used in food and industry, is collagen that has been irreversibly hydrolyzed. Collagen also has many medical uses in treating complications of the bones and skin.
The name collagen comes from the Greek, meaning "glue", denoting "producing". This refers to the compound's early use in the process of boiling the skin and tendons of horses and other animals to obtain glue.
When hydrolyzed, collagen is reduced to small peptides which can be ingested in the form of dietary supplement or functional foods and beverages with intent to aid joint and bone health and enhance skin health.Hydrolyzed collagen has a much smaller molecular weight in comparison to native collagen or gelatin, study suggests that more than 90% of hydrolyzed collagen is digested and available as small peptides in the blood stream within one hour. From the blood the peptides (containing hydroxyproline) are transported into the target tissues, e.g. skin, bones and cartilage, where the peptides act as building blocks for local cells and help boost the production of new collagen fibers.
Use of collagen Collagen is a high molecular functional protein.It is the main component of the skin, accounting for 80% of the dermis.It forms a fine elastic net in the skin that firmly traps moisture and supports the skin.Collagen is a coiled fibrous protein composed of three ...
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