Quick Details:
Product Name: Ropinirole
Chemical name/Alias: SKF-101468;SKF-101468A;ReQuip
CAS NO: 91374-21-9
Appearance: white powder
MF: C16H24N2O
Purity: 99%
Origin: China
Export market: Global
Grade: Pharmaceutical grade
Supply capacity: Mass in stock.
Usage: Health care products
Description:
Ropinirole (trade names Requip, Repreve, Ronirol, Adartrel) is a dopamine agonist of the non-ergoline class of medications. It is used in the treatment of Parkinson's disease and restless legs syndrome (RLS). Ropinirole is one of three medications approved by the FDA to treat RLS, the other two being pramipexole (Mirapex) and gabapentin enacarbil (Horizant). The discovery of the drug's utility in RLS has been used as an example of successful drug repurposing.
Ropinirole's patent expired in May 2008, and the drug is now available in generic form.
Medical uses
Ropinirole is prescribed for mainly Parkinson's disease, RLS and extrapyramidal symptoms. It can also reduce the side effects caused by selective serotonin reuptake inhibitors, including Parkinsonism syndrome as well as sexual dysfunction and erectile dysfunction caused by either SSRIs or antipsychotics.
Dosage
Ropinirole in the Requip form is available in various preparations, ranging from a 0.25 mg tablet to a 5 mg tablet. The primary reason is dose titration. This implies that the person taking Requip has to closely interact and communicate with the primary care physician with regard to how much should actually be taken by the patient.
For Parkinson's disease, the maximum recommended dose is 24 mg per day, taken in three separate doses spread throughout the day. The maximum dose recommendations of ropinirole for subjects with end stage renal disease (ESRD) should be reduced by 25% compared with those recommended for subjects with normal renal function. A 25% dose reduction represents a more straightforward dosage regimen in terms of available tablet strength, compared with a 30% dose reduction.
Side effects:
Ropinirole can cause nausea, dizziness, hallucinations, orthostatic hypotension, and sudden sleep attacks during the daytime. Unusual side effects specific to D3 agonists such as ropinirole and pramipexole can include hypersexuality, punding and compulsive gambling, even in patients without a history of these behaviours.
Quick Details: Product Name: Ropinirole Chemical name/Alias: SKF-101468;SKF-101468A;ReQuip CAS NO: 91374-21-9 Appearance: white powder MF: C16H24N2O Purity: 99% Origin: China Export market: Global Grade: Pharmaceutical grade Supply capacity: Mass in stock. Usage: Health care ...