Promethazine hydrochloride

Product Name: Promethazine hydrochloride

Alias: 10-(2-dimethylamino-1-propyl)phenothiazine hydrochloride

CAS NO: 58-33-3

Appearance: white powder

MF: C17H21ClN2S

Usage: antihistamines

Description:

Promethazine is a neuroleptic medication and first-generation antihistamine of the phenothiazine family. The drug has strong sedative and weak antipsychotic effects. It also reduces motion sickness and has antiemetic (via its action on the dopamine receptor D2) and anticholinergic properties. In some countries it is prescribed for insomnia when benzodiazepines are contraindicated. It is available in many countries under many brand names. Promethazine was developed in the mid 1940s when a team of scientists from Rhône-Poulenc laboratories were able to synthesize it from phenothiazine and a diamine side chain of diphenhydramine.