S4 Andarine
Muscle Wasting Treatment S4 Andarine CAS 401900-40-1
Synonyms: Andarine, Andarin, S-4, S-40503, GTx-007
IUPAC-Name:(2S)-3-(4-acetamido-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide
CAS: 401900-40-1
MF: C19H18F3N3O6
Half Life: 2.6 hours.
Melting Point: 70-74 °C
Storage: Room temperature
Appearance: Pale yellow fine powder, odorless, acrid bitter taste
Solubility: Soluble in DMSO (85 mg/mL), Water (< 1.2 mg/mL), and Ethanol (85 mg/mL), it is also soluable in Propylene Glycol and PEG400.
Great effect of S4 Andarine :
1. 1/3 as androgenic as testosterone in muscle tissue.
2. Anabolic at doses above 50mg
3. Great for strength
4. Great for muscle hardness
5. Great for enhanced vascularity
6. Great for endurance (aerobic or anaerobic)
7. Accelerated fat loss above 50mg
8. Joint healing effects
Description:
Andarine is an orally active partial agonist for androgen receptors, S-4 is effective in not only maintaining lean body mass but actually increasing it. Andarine is less potent in both anabolic and
androgenic effects than other SARMs. In an animal model of benign prostatic hypertrophy, andarine was shown to reduce prostate weight with similar efficacy to finasteride, but without producing any
reduction in muscle mass or anti-androgenic side effects. This suggests that it is able to competitively block binding of dihydrotestosterone to its receptor targets in the prostate gland, but its
partial agonist effects at androgen receptors prevent the side effects associated with the anti-androgenic drugs traditionally used for treatment of BPH.
Usage:
Andarine (GTx-007, S-4) is an investigational selective androgen receptor modulator (SARM) developed by GTX, Inc for treatment of conditions such as muscle wasting, osteoporosis and benign
prostatic hypertrophy, using the non-steroidal androgen antagonist bicalutamide as a lead compound.
Andarine is an orally active partial agonist for androgen receptors. It is less potent in both anabolic and androgenic effects than other SARMs. In an animal model of benign prostatic hypertrophy,
andarine was shown to reduce prostate weight with similar efficacy to finasteride, but without producing any reduction in muscle mass or anti-androgenic side effects.
This suggests that it is able to competitively block binding of dihydrotestosterone to its receptor targets in the prostate gland, but its partial agonist effects at androgen receptors prevent the
side effects associated with the anti-androgenic drugs traditionally used for treatment of BPH.
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