Praziquantel

CAS 55268-74-1 Praziquantel

Product Name: Praziquantel

CAS: 55268-74-1

EINECS: 259-559-6

MF: C19H24N2O2

MW: 312.41

Assay: 99%

Appearance: White powder

Praziquantel, marketed as Biltricide, is an anthelmintic used in humans and animals for the treatment of tapeworms and flukes. Specifically, it is effective against schistosoma, Clonorchis sinensis the fish tapeworm Diphyllobothrium latum.

It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.

Praziquantel is used to treat diseases in humans, mammals, and fish that are caused by infection with several types of internal/gastrointestinal, and external parasites, including:

1)Salmon poisoning disease

2)Hydatid disease caused by infection of various organs with larval stages of tapeworms of the genus Echinococcus

3)Cysticercosis caused by infection of the brain and/or muscles with the eggs and larvae of the pork tapeworm Taenia solium (though it has been judged less effective than albendazole in treatment of neurocysticercosis)

4)In cats and dogs whose gastrointestinal tract is infected with the tapeworms Dipylidium caninum or Taenia taeniaeformis, respectively; praziquantel is also often used in fixed combination with pyrantel embonate against the roundworms (ascarids): Toxocara cati and Toxascaris leonina.Praziquantel is also effective against Echinococcus multilocularis.

5)Schistosomiasis caused by trematodes of the genus Schistosoma. As of 2005, praziquantel is the primary treatment for human schistosomiasis, for which it is usually effective in a single dose.

6)Clonorchiasis brought on by the Chinese liver fluke Clonorchis sinensis

7)Paragonimiasis caused by infection with lung flukes, mostly of the species Paragonimus westermani[citation needed]

8)Fasciolopsiasis caused by intestinal fluke Fasciolopsis buski

9)Diplozoon paradoxum and other Trematoda infections of many fish species