Product Name: Bortezomib
Synonyms: VELCADE;dpba;BORTEZOMIB;[(1r)-3-methyl-1-[[(2s)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]-boronic acid;VELCADE(BORTEZOMIB);Boronic acid,
B-[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-;Bortezomib for research;Bortezomib ( Velcade, MG-341, PS-341 )
CAS: 179324-69-7
MF: C19H25BN4O4
MW: 384.24
Product Categories: Boron Derivatives;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Pepetides;ProteasomeInhibitors;Apis;Inhibitor;Final material;API;peptides
mp 122-124°C
density 1.214
storage temp. Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Stability: Hygroscopic and Moisture Sensitive
Chemical Properties :Yellow Solid
Usage: Bortezomib is the first proteasome inhibitor to be approved b the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein
particle found in the nucleus and cytosol of all eukaryotic cells. T
Usage Bortezomib is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein
particle foun d in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.
Usage selective proteasome inhibitor .