Rimonaban

Product name :Rimonaban

Synonyms: ACOMPLIA;RIMONABANT;RIMONABANT(ACOMPLIA,SR141716);5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidinopyrazole-3-carboxamide;1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-;5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide;A 281;Sr 141716

CAS: 168273-06-1

MF: C22H21Cl3N4O

MW: 463.79

Product Categories: Weight Loss;SR141716

Mol File: 168273-06-1.mol

Usage: Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane ; Mainly used for weight loss .

Product description:

Rimonabant is a weight loss drug, Sanofi-Aventis by the French company successfully developed for the treatment of obesity is the first cannabinoid type 1 receptor (CB1) antagonist, by selectively blocking the EC system cannabis Su -1 (cannabinoid-1, CB1) receptors play a role, can significantly reduce weight, reduce waist circumference, reducing risk factors for cardiovascular disease, but also can improve blood lipids and insulin resistance and metabolic syndrome, especially for the existence of clinical obesity or heart disease risk for people.