Sodium Butyrate

Country: United States
Market: Africa,Americas,Emerging Markets,Asia,European Union,Middle East
Founded Year: 2005
Address: 45-1 Ramsey Road Shirley
Contact: Lisa Clara

Sodium butyrate is a compound with formula Na(C3H7COO). It is the sodium salt of butyric acid. It has various effects on cultured mammalian cells including inhibition of proliferation, induction of differentiation and induction or repression of gene expression. As such, it can be used in lab to bring about any of these effects. Specifically, butyrate treatment of cells results in histone hyperacetylation, and butyrate itself inhibits HDAC activity. Butyrate has been an essential vehicle for determining the role of histone acetylation in chromatin structure and function. Inhibition of HDAC activity affects the expression of only 2% of mammalian genes.