HYDROCORTISONE 50-23-7

Basic information of Hydrocortisone 50-23-7

• Product Name: Hydrocortisone
• Molecular Formula: C21H30O5
• Molecular Weight: 362.46
• CAS No.: 50-23-7
• Appearance: White crystalline powder
• Specifications: EP6/USP37;EP8

Usage of Hydrocortisone 50-23-7

• Treat for allergic dermatitis, eczema, neurodermatitis, seborrheic dermatitis, etc.
• Adrenocortical insufficiency and hypopituitarism.

COA of Hydrocortisone 50-23-7

SINOWAY INDUSTRIAL CO.,LTD.
16/F.,HUICHENG COMM.COMPLEX, 839 XIAHE RD.,XIAMEN,CHINA
TEL: 0086-592-5854962 POSTCODE: 361004
FAX: 0086-592-5854960 E-MAIL: sale3@china-sinoway.com
Certificate of Analysis
Product Name: Hydrocortisone
Batch No.: T2930
Manuf. Date: 2014-03-16
Retest Date: 2017-03-15
Report Date: 2014-04-09

Items	Specifications	Results
Appearance	A white or almost white,crystalline powder	Whitecrystalline powder
Solubility	Practically insoluble in water, sparingly soluble in acetone and in alcohol, slightly in methylene chloride	Complies
Identification
A: IR-Spectrum	Meets the requirement	Complies
B: HPLC	Meets the requirement	Complies
Specific optical rotation	Between+162°and +168°	+165.4°
Loss on drying	Not more than 1.0%	0.09%
Related substances
Impurity D RRT0.2	Not more than 0.50%	0.23%
Impurity H RRT0.3	Not more than 0.15%	N.D
Impurity I RRT0.5	Not more than 0.50%	0.17%
Impurity M RRT0.7	Not more than 0.10%	0.09%
Impurity G RRT0.8	Not more than 0.40%	0.08%
Impurity E RRT0.86	Not more than 0.50%	0.09%
Impurity A RRT0.96	Not more than 0.20%	0.09%
Impurity B RRT1.1	Not more than 0.20%	N. D
Impurity F RRT1.4	Not more than 0.30%	0.06%
Impurity C RRT1.5	Not more than 0.50%	0.08%
Impurity N RRT1.7	Not more than 0.15%	N.D
Any unspecified impurity	Not more than 0.10%	Complies
Sum of impurities	Not more than 2.0%	1.01%
Assay	Between 97.0% and 103.0%	100.7%
Residual solvents (in-house)
Methanol	Not morethan 500ppm	Not detect out
Ethanol	Not more than 2000ppm	Not detect out
Methylene chloride	Not more than 600ppm	Not detect out
Chloroform	Not more than 60ppm	Not detect out
Particle size (In-house )	90% not more than 15micron	Complies
Conclusion	The product conforms to Ph.Eur. 8.0

• Sinoway Industrial Co., Ltd.
• Tel:+86-0592-5854962
• Fax:+86-0592-5854960
• Email:xie@china-sinoway.com
• WEB:http://www.china-sinoway.com/products/hydrocortisone-powder-50-23-7.html