CAS 609799-22-6 Tasimelteon

CAS 609799-22-6 Tasimelteon

Product Name:Tasimelteon

Alias:Hetlioz

CAS NO.:609799-22-6

Molecular Formula:C15H19NO2

Molecular Weight:245.32

Purity:99%

Appearance:White Powder

Grade:Pharmaceutical Grade

Development

Tasimelteon was developed for the treatment of insomnia and other sleep disorders. A phase II trial on circadian rhythm sleep disorders was concluded in March 2005. A phase III insomnia trial was conducted in 2006. A second phase III trial on insomnia, this time concerning primary insomnia, was completed in June 2008. In 2010, the FDA granted orphan drug status to tasimelteon, then regarded as an investigational medication, for use in totally blind adults with N24HSWD.

On completion of Phase III trials, interpretations of the clinical trials by the research team concluded that the drug may have therapeutic potential for transient insomnia in circadian rhythm sleep disorders. A year-long (2011-2012) study at Harvard tested the use of tasimelteon in blind subjects with non-24-hour sleep-wake disorder. The drug has not been tested in children nor in any non-blind people.