Remarks: |
Soluble in Water,Methyl alcoho.Ethyl acetate alcohol,Methylene chloride Hydrocarbon. .Kept away form light in scaled containers at low temperature under neutral or faint basic conditions. .NVP had average toxicity and faint odor.It is corrosicve to rubber and leather.Be sure not to enter eyes or spray to skin. .NVP can self-polymerize when shaken or preserved for a long time or under illumination,so the antipolymerizer is needed,which should be distilled befroe use. |
NVP-BGJ398(BGJ-398) is a novel selective, pan-specific FGFR inhibitor with IC50 of 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively; >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, ...
BKM120 is an orally bioavailable specific oral inhibitor of the pan-class I phosphatidylinositol 3 kinase (PI3K) family of lipid kinases with potential antineoplastic activity. Buparlisib specifically inhibits class I PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling ...