CAS 6700-34-1 Dextromethorphan Hydrobromide
Product Name:Dextromethorphan Hydrobromide
Alias: Romilar,dextromethorphan,Demorphine,Dormetan
CAS No.: 125-69-9
EINECS No.: 204-750-1
MF: C18H26BrNO
MW: 352.31
Purity: 98.0%
Appearance: White or kind of white crystalline powder
Grade:Pharmaceutical Grade
Dextromethorphan (DXM or DM) is an antitussive (cough suppressant) drug. Dextromethorphan has also found other uses in medicine, ranging from pain relief to psychological applications. It is sold
in syrup, tablet, spray, and lozenge forms. In its pure form, dextromethorphan occurs as a white powder.
DXM is also used recreationally. When exceeding label-specified maximum dosages, dextromethorphan acts as a dissociative hallucinogen. Its mechanism of action is via multiple effects, including
actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist.DXM and its major metabolite, dextrorphan, also acts as an NMDA receptor antagonist at high doses, which
produces effects similar to, yet distinct from, the dissociative states created by other dissociative anaesthetics such as ketamine and phencyclidine. As well, the metabolite 3-methoxymorphinan of
dextrorphan (thus a second-level metabolite of DXM) produces local anesthetic effects in rats with potency above dextrorphan, but below that of DXM.
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