Proparacaine Hydrochloride for Ophthalmic Surface Anesthesia
Product Quick Detail
- FOB Price
- USD $70.00 / Piece
- Place Of Origin
- China (Mainland)
- Minimum Order
- 1
- Packaging
- 1kg/foil bag
- Delivery
- 15 Days
Specifications
Product Name:Proparacaine hydrochloride
Synonyms:PROPARACAINE HCl; heracaine
CAS:5875-06-9
Molecular formula:C16H27ClN2O3
Molecular Weight:330.85
EINECS number:227-541-7
country of origin:China
Quality StandardsEnterprise Standard/Pharma Grade
StorageBupivacaine injection should be kept protected from light and should not be allowed to freeze. Ampoules should not be used if the solution is discoloured.
Synonyms:PROPARACAINE HCl; heracaine
CAS:5875-06-9
Molecular formula:C16H27ClN2O3
Molecular Weight:330.85
EINECS number:227-541-7
country of origin:China
Quality StandardsEnterprise Standard/Pharma Grade
StorageBupivacaine injection should be kept protected from light and should not be allowed to freeze. Ampoules should not be used if the solution is discoloured.
Description
1.Proparacaine Hydrochloride Ophthalmic Solution is a rapid acting local anesthetic suitable for ophthalmic use. With a single drop, the onset of anesthesia begins within 30 seconds and persists for 15 minutes or longer.
2.The main site of anesthetic action is the nerve cell membrane where proparacaine interferes with the large transient increase in the membrane permeability to sodium ions that is normally produced by a slight depolarization of the membrane. As the anesthetic action progressively develops in a nerve, the threshold for electrical stimulation gradually increases and the safety factor for conduction decreases; when this action is sufficiently well developed, block of conduction is produced.
3.The exact mechanism whereby proparacaine and other local anesthetics influence the permeability of the cell membrane is unknown; however, several studies indicate that local anesthetics may limit sodium ion permeability by closing the pores through which the ions migrate in the lipid layer of the nerve cell membrane. This limitation prevents the fundamental change necessary for the generation of the action potential.
Dosage
The anesthetic intensity of the drug is slightly higher than the same concentration of tetracaine, and the effect is fast. Since the structure is different from procaine and tetracaine, there is no cross-sensitization with other local anesthetics, and it rarely causes initial stimuli. Pregnant women and lactating women should be used with caution.
1.Proparacaine Hydrochloride Ophthalmic Solution is a rapid acting local anesthetic suitable for ophthalmic use. With a single drop, the onset of anesthesia begins within 30 seconds and persists for 15 minutes or longer.
2.The main site of anesthetic action is the nerve cell membrane where proparacaine interferes with the large transient increase in the membrane permeability to sodium ions that is normally produced by a slight depolarization of the membrane. As the anesthetic action progressively develops in a nerve, the threshold for electrical stimulation gradually increases and the safety factor for conduction decreases; when this action is sufficiently well developed, block of conduction is produced.
3.The exact mechanism whereby proparacaine and other local anesthetics influence the permeability of the cell membrane is unknown; however, several studies indicate that local anesthetics may limit sodium ion permeability by closing the pores through which the ions migrate in the lipid layer of the nerve cell membrane. This limitation prevents the fundamental change necessary for the generation of the action potential.
Dosage
The anesthetic intensity of the drug is slightly higher than the same concentration of tetracaine, and the effect is fast. Since the structure is different from procaine and tetracaine, there is no cross-sensitization with other local anesthetics, and it rarely causes initial stimuli. Pregnant women and lactating women should be used with caution.
- Country: China (Mainland)
- Business Type:
- Market:欧洲,美洲,亚洲,大洋洲
- Founded Year:2017
- Address:
- Contact:su sylvia
