Description
The growth of WEHI-3 is inhibited by 4 ng/ml LPS and blocked by higher concentrations. Dextran sulfate at 30 to 40 ng/ml also inhibits growth. Latex beads are phagocytized but are not toxic.
Zymosan and BCG are phagocytized and block growth. The cells exhibit only weak effector activity in antibody dependent cell mediated cytotoxicity.
Organism
Mus musculus (mouse)
Karyotype
Murine hypotetraploid karyotype with 19% polyploidy - 73/74(70-79)<4n> - 2-3 centric fusion markers present.
Source
Blood, peripheral; leukemia
Culture Properties
suspension
Morphology
small, round, single cells growing adherently and partly in suspension
https://www.creative-bioarray.com/WEHI-3B-CSC-C1058-item-1526.htm