Description
Established from a tumor in a female BALB/c mouse in 1968; cells were described to synthesize lysozyme and interleukin-1 and to have receptors for immunoglobulin and complement. Active in
antibody dependent phagocytosis; growth is inhibited by extran sulfate, PPD and LPS; tested and found negative for ectromelia virus (mousepox).
Karyotype
Cytogenetics: murine hypotetraploid karyotype - 78(70-81) - in most cells a centric fragment was present - mouse chromosome morphology confirmed
Source
monocytes-macrophages
https://www.creative-bioarray.com/J774A1J-774A1-CSC-C1074-item-1540.htm