SGT78
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CUMYL-4CN-BINACA (also known as CUMYL-CYBINACA or SGT-78) is an indazole-3-carboxamide based synthetic cannabinoid that has been sold online as a designer drug. It is a potent agonist for cannabinoid receptors CB1and CB2, within vitroEC50values of 0.58 nM and 6.12 nM, respectively. In mice, CUMYL-4CN-BINACA produces hypothermic andpro-convulsant effects via the CB1receptor,[7] and anecdotal reports suggest it has an active dose of around 0.1 mg in humans.