118-42-3 hydroxychloroquine

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hydroxychloroquine Biological Activity

Description Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro[1][2][3].
Related Catalog
Signaling Pathways
Research Areas
Research Areas
Signaling Pathways
Signaling Pathways
References [1]. Manzo C, et al. Psychomotor Agitation Following Treatment with Hydroxychloroquine. Drug Saf Case Rep. 2017 Dec;4(1):6.

[2]. Lamphier M, et al. Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo. Mol Pharmacol. 2014 Mar;85(3):429-40.

[3]. Yao X, et al. In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Clin Infect Dis. 2020 Mar 9. pii: ciaa237.

Chemical & Physical Properties

Density 1.176 g/cm3
Boiling Point 516.7ºC at 760 mmHg
Melting Point 89-91°
Molecular Formula C18H26ClN3O
Molecular Weight 335.87200
Flash Point 266.3ºC
Exact Mass 335.17600
PSA 48.39000
LogP 3.85600
Vapour Pressure 1.68E-11mmHg at 25°C
Index of Refraction 1.5790 (estimate)
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747-36-4  Hydroxychloroquine sulfate
747-36-4 Hydroxychloroquine sulfate

Description Hydroxychloroquine sulfate is a synthetic antimalarial drug which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Related Catalog Signaling Pathways Signaling Pathways Research Areas Research Areas Target Antimalarial[1], TLR7/9[2] In Vitro ...

SHHANGHAI DUMI BIOTECNOLOGY CO.,LTD

CAS 747-36-4 Hydroxychloroquine sulfate (lily whatsapp +8619930501653
CAS 747-36-4 Hydroxychloroquine sulfate (lily whatsapp +8619930501653

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