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Trade name: Spinraza ATC code: M09AX07 (WHO) Elimination half-life: 135–177 days (in CSF), 63–87 days (in plasma) License data: EU EMA: by INN Metabolism: Exonuclease (3’- and 5’)-mediated hydrolysis Synonyms: IONIS-SMNRx, ISIS-SMNRx ...