Etomidate CAS Number 33125-97-2

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Use of Etomidate


Etomidate(R-16659) is a GABAA receptors agonist, which is a short acting intravenous anaesthetic agent used for the induction of general anaesthesia.Target: GABA ReceptorEtomidate is a potent inhibitor of the adrenal response to surgery. The absence of clinical consequences associated with the blunted response suggests that a major increase in adrenal hormone production may not be necessary during surgery [1]. Etomidate is an intravenous induction agent that is associated with hemodynamic stability during intubation. The agent is therefore attractive for use in critically ill patients who have a high risk of hemodynamic instability during this procedure [2]. Etomidate use was not associated with all cause 28-day mortality or hospital mortality but was associated with significantly higher ICU mortality (91% vs. 64% for etomidate and controls groups, respectively; p =0.02). Etomidate patients who received subsequent doses of hydrocortisone required lower doses of vasopressors and had more vasopressor-free days but no improvement in mortality [3].Clinical indications: FDA Approved Date: 1983Toxicity: Undesirable side effects of etomidate that may limit its use include pain on injection, myoclonus and adrenocortical suppression lasting 4-6 hours following an induction dose.
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CAS  33125-97-2  etomidate
CAS 33125-97-2 etomidate

Please add Telegram Telegram:@qqmmnn1 threema:CBN7YHWW signal/skype:+447852425006 Email:a7788509386@gmail.com At present, our products are exported to the United States, Japan, the Netherlands, Europe, Southeast Asia and other countries and regions, favored by customers.If ...

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2-methyl-3-phenyl-oxirane-2-carboxylic acid CAS Number	5449-12-7
2-methyl-3-phenyl-oxirane-2-carboxylic acid CAS Number 5449-12-7

Common Name 2-methyl-3-phenyl-oxirane-2-carboxylic acid CAS Number 5449-12-7 Molecular Weight 201.17400 Density 1.28g/cm3 Boiling Point 334.3ºC at 760 mmHg Molecular Formula C10H10NaO3+ Melting Point N/A MSDS N/A Flash Point 136.7ºC Density 1.28g/cm3 Boiling Point 334.3ºC at ...

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33125-97-2  etomidate
33125-97-2 etomidate

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