High quality Hemin CAS Number 16009-13-5

Heme chloride action

Combines with oxygen

The way heme binds to oxygen is an amazing process.First a oxygen and hemoglobin a combination of the four subunits, combines with oxygen after pearl protein structure change, causing the structure change of hemoglobin, this change makes the second oxygen compared with the first oxygen molecules are more likely to look for the another of heme binding, and it will further promote the combination of the combination of the third oxygen molecules,And so on until the four subunits that make up heme are bound to each of the four oxygen molecules.The same is true when oxygen is released from tissues. The departure of one oxygen molecule stimulates the departure of another until all oxygen molecules are released. This interesting phenomenon is called synergism.

Hemoglobin molecular structure due to the synergistic effect, the combination of hemoglobin and oxygen in an s-shaped curve shape, in a specific range as the change of oxygen content in the environment, the combination of hemoglobin and oxygen rate has a dramatic change, the process of biological tissue in the body of the oxygen concentration, and oxygen concentration in the lung tissue at the both sides of the mutation, thus in the lung tissue,The heme is sufficiently bound to oxygen to release the oxygen molecules it carries in the rest of the body.But when oxygen levels in the environment very high or very low, hemoglobin oxygen curve is very flat, oxygen concentration in the huge fluctuations may not be able to make the combination of hemoglobin and oxygen rate changed significantly, so healthy people even breathing pure oxygen, blood will not significantly improve capacity for carrying oxygen, from this perspective,To healthy person character of the place THAT ABSORB oxygen produces PSYCHOLOGICAL hint to WANT TO be FAR greater THAN its physiological effect.When THE RED BLOOD CELL INSIDE BLOOD IS DESTROYED TOO MUCH, LIVER LOAD INCREASES THE TRANSPORT INSIDE LIVER CELL, COMBINE AND EXCRETION OBSTACLE, OR EXTRAHEPATIC BILIARY TRACT IS BLOCKED, CAN CAUSE BILIRUBIN CONCENTRATION INSIDE BLOOD TO INCREASE AND APPEAR JAUNDICE