Tirzepatide (LY3298176)
Product Quick Detail
- FOB Price
- USD $100.00 / Piece
- Place Of Origin
- denmark
- Minimum Order
- 1
- Packaging
- discreet
- Delivery
- 5 Days
Specifications
Tirzepatide hydrochloride (LY3298176 hydrochloride) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist that is being developed for the treatment of type 2 diabetes [1] .
In HEK293 cells, Tirzepatide induces internalization of the GIPR and has a propensity toward partial agonism, and this ultimately reflects in signaling bias toward the cAMP pathway versus β-arrestin recruitment. [1] LY3298176 shows glucose-dependent insulin secretion and improves glucose tolerance by acting on both GIP and GLP-1 receptors in mice.
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