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Also known as: 164656-23-9; Avodart; GG-745; UNII-O0J6XJN02I; GI-198745; CHEBI:521033; Avolve; Duagen; Avodart (TN)

Name: Dutasteride

CAS No. 164656-23-9

Solubility soluble in ethanol (44 mg/mL), methanol (64 mg/mL) and polyethylene glycol 400 (3 mg/mL), but it is insoluble in water

Molecular Weight 528.53

Formula C27H30F6N2O2

Density 1.303 g/cm3

Appearance white crystalline solid

Boiling Point 620.3 °C at 760 mmHg

Dutasteride is used alone or with another medication (tamsulosin [Flomax]) to treat benign prostatic hyperplasia (BPH; enlargement of the prostate gland). Dutasteride is used to treat symptoms of BPH and may reduce the chance of developing acute urinary retention (sudden inability to urinate). Dutasteride may also decrease the chance that prostate surgery will be needed. Dutasteride is in a class of medications called 5-alpha reductase inhibitors. It works by blocking the production of a natural substance that enlarges the prostate.