Yohimbine HCl 65-19-0

Yohimbine HCl (Extract)

CAS NO: 65-19-0

Plant original: Pausinystalia Yohimbe

Specifications: 8~98% Yohimbine HCL by HPLC

Molecular Formula: C21H27ClN2O

Molecular Weight: 390.904

Indications and Uses

Yohimbine hydrochloride is indicated as a sympathicolytic and mydriatic. It may have activity as an aphrodisiac.

Impotence (not able to have erections)

The way yohimbine works is not known for sure. It is thought, however, to work by increasing the body's production of certain chemicals that help produce erections. It does not work in all men who are impotent.

New research that shows it could be an herb with very effective antioxidant potential. Research shows it is a vasodilator, which means that it increases blood flow to the extremities and appendages.

Safety Concerns

Patients sensitive to rauwolfia alkaloids such as deserpidine, rauwolfia serpentina, or reserpine may also be sensitive to yohimbine.

Yohimbine readily penetrates the (CNS) and produces a complex pattern of responses in lower doses than those required to produce peripheral alpha-adrenergic blockade. These include, anti-diuresis, a general picture of central excitation including elevation of blood pressure and heart rate, increased motor activity, nervousness, irritability and tremor. Sweating, nausea and vomiting are common after parenteral administration of the drug. Also, dizziness, headache skin flushing reported when used orally.

Generally, this drug is not proposed for use in females and certainly must not be used during pregnancy. Neither is this drug proposed for use in pediatric, geriatric or cardio-renal patients with gastric or duodenal ulcer history. Nor should it be used in conjunction with mood- modifying drugs such as antidepressants, or in psychiatric patients in general.

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