Nicotinamide CAS 98-92-0 / SKYPE wt1990iris(OAP-070)

Nicotinamide

Product Name: Nicotinamide

Synonym: Pyridine-3-carboxamide; niacinamide cell culture tested; Nicotinamide (1.06818); Niacinamide; Vitamin PP; VPP; Pyridine-3-Carboxyamide; 3-Pyridinecarboxyamide; Vitamin B3; Nicotinic acid amide;;

Nicotinamide CAS No.: 98-92-0

Nicotinamide EINECS No.: 202-713-4

Nicotinamide Molecular formula: C6H6N2O

Nicotinamide Molecular weight: 122.12

Nicotinamide Packing: 25KG/Drum

Nicotinamide Content: 99%

Nicotinamide Appearance: white powder

Nicotinamide Category: food additive

Nicotinamide Product Description

Nicotinamide, also known as niacinamide and nicotinic amide, is the amide of nicotinic acid (vitamin B3 / niacin). Nicotinamide is a water-soluble vitamin and is part of the vitamin B group. Nicotinic acid, also known as niacin, is converted to nicotinamide in vivo, and, though the two are identical in their vitamin functions, nicotinamide does not have the same pharmacological and toxic effects of niacin, which occur incidental to niacin's conversion. Thus nicotinamide does not reduce cholesterol or cause flushing, although nicotinamide may be toxic to the liver at doses exceeding 3 g/day for adults. In cells, niacin is incorporated into nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP), although the pathways for nicotinic acid amide and nicotinic acid are very similar. NAD+ and NADP+ are coenzymes in a wide variety of enzymatic oxidation-reduction reactions. It's produced by the aqueous aminolysis of 3-cyanopyridine (nicotinonitrile) and subsequent crystallization.

Nicotinamide Use in medicine

Skin conditions

Nicotinamide has demonstrated anti-inflammatory actions that may be of benefit to patients with inflammatory skin conditions.These conditions include acne vulgaris, and the compound can suppress antigen-induced, lymphocytic transformation and inhibit 3',5'-cyclic-AMP phosphodiesterase. Nicotinamide has demonstrated the ability to block the inflammatory actions of iodides known to precipitate or exacerbate inflammatory acne.

Anxiety

Studies show that nicotinamide has anxiolytic (anti-anxiety) properties. It may work in a way
.

Food Sources

Nicotinamide occurs in trace amounts mainly in meat, fish, nuts, and mushrooms, as well as to a lesser extent in some vegetables.

Function:

A - For coronary heart disease, viral myocarditis, rheumatic heart disease, and a few digitalism with arrhythmia ( mostly application after other drug is invalid )

B- General has the obvious curative effect to various degree atrioventricular block.
C- Used as a cosolvent and stabilizer in the medicament.