Description:
Tadalafil
Alias: Tadalafei;Cialis
CAS No: 171596-29-5
MF: C22H19N3O4
MW: 389.41
Purity: 99.5%
Appearance: white powder, odorless, tasteless, insoluble in water and alcohol.
Applications:
Cialis (tadalifil) is the second-generation Viagra, more or less. While the little blue pill may work to give you an erection for 6-8 hours, Cialis is good for 36-48 hours. This obviously makes it
much more practical. Why are we talking about this? I doubt anyone using endogenous testosterone would need to consider the use of such a compound, but this drug can still have some uses during
post cycle therapy. A lot of men find that once they go off steroids and begin post cycle therapy (PCT), they suffer reduced libido as well as erectile dysfunction. Cialis may be useful for helping
this, at least during PCT.
The efficacy and safety of tadalafil for the treatment of erectile dysfunction was assessed in a 6-month study. Men with mild, moderate or severe ED were given tadalafil (20 mg) as needed or
placebo ("any minute now, baby, no, really"). Tadalafil significantly improved erectile function compared with placebo (which only succeeded in embarrassing the men who took it and tried to get
laid). At the end of the study, sexual intercourse attempts success rate for those using Cialis was 73.5% (this only refers to the ability to achieve erection and have intercourse, not the actual
success rate of those attempting to get laid on a given night)
Although sildenafil (Viagra), vardenafil (Levitra), and tadalafil (Cialis) all work by inhibiting PDE5, tadalafil's pharmacologic distinction is its longer half-life (17.50 hours) - compared to
sildenafil (4.0-5.0 hours) and vardenafil (4.0-5.0 hours) - resulting in longer duration of action, and so partly responsible for "The Weekend Pill" sobriquet. Furthermore, the longer half-life is
the basis for current investigation of tadalafil's daily therapeutic use in relieving pulmonary arterial hypertension. Sildenafil is approved in several world regions as a thrice-daily therapy for
pulmonary arterial hypertension.
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