Desonide

Desonide

English Synonyms: PREDNACINOLONE;DESONIDE;1,4-PREGNADIEN-11-BETA, 16-ALPHA, 17,21-TETROL-3,20-DIONE 16,17-ACETONIDE;(11b,16a)-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-pregna-1,4-diene-3,20-dione;16-alpha-hydroxyprednisole-16,17-acetonide;17-acetonide,16-alpha-hydroxy-prednisolone-1;d-2083;steroderm
CAS NO.: 638-94-8
Assay: 99%
Product Categories:steriods
Appearance:white powder
Molecular Formula:C24H32O6
Molecular Weight:416.51
EINECS:211-351-6
Packing:foil bag
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Usage: With acetal-based adrenal cortex hormones

Place of Origin: China
Certification: ISO9001; ISO14000
Payment & Shipping Terms:Minimum Order Quantity: 1kg
Packaging Details: 100g/bag, 500g/bag, 1kg/bag
Delivery Time: 1-3 work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 100kg/month

Desonide - Clinical Pharmacology
Like other topical corticosteroids, Desonide has anti-inflammatory, antipruritic, and vasoconstrictive properties. The mechanism of the anti-inflammatory activity of the topical steroids, in general, is unclear. However corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called, lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2.

Uses
This medication is used to treat a variety of skin conditions (e.g., eczema, dermatitis,allergies, rash). Desonide reduces the swelling, itching and redness that can occur in these types of conditions. Desonide is a mild corticosteroid.Desonide Ointment, 0.05% is a low potency corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses.
It should not be used for longer than two weeks unless directed by a physician.

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