2-Ketoglutaric acid CAS:328-50-7
Product Quick Detail
- Place Of Origin
- HuNan
- Packaging
- Foil Bag or Tin
- Delivery
- 7 Days
Specifications
2-Ketoglutaric acid
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CAS:328-50-7
MF: C5H6O5
MW: 146.1
Purity:99%
mp 113-115 °C
Functions:
Krebs cycle
α-Ketoglutarate is a key intermediate in the Krebs cycle, coming after isocitrate and before succinyl CoA. Anaplerotic reactions can replenish the cycle at this juncture by synthesizing
α-ketoglutarate from transamination of glutamate, or through action of glutamate dehydrogenase on glutamate.
Formation of amino acids
Glutamine is synthesized from glutamate by glutamine synthetase, which utilizes an ATP to form glutamyl phosphate; this intermediate is attacked by ammonia as a nucleophile giving glutamine and
inorganic phosphate.
Dietary supplement
α-Ketoglutaric acids is sold as a dietary supplement and to body builders as AKG or a-KG with the claim that it improves peak athletic performance. This claim is based on studies that show excess
ammonia in the body can combine with alpha-ketoglutarate, reducing problems associated with ammonia toxicity.However, the only studies that show alpha-ketoglutarate can reduce ammonia toxicity have
been performed in hemodialysis patients.
Longevity
A study released on May 14, 2014 links α-ketoglutarate with significantly increased lifespan in nematode worms. Its anion, α-ketoglutarate (α-KG, also called oxo-glutarate) is an important
biological compound. It is the keto acid produced by deamination of glutamate, and is an intermediate in the Krebs cycle.
Usage:
Determination of amino-converting enzyme dehydrogenase substrate reagents measuring liver function, also used as intermediates in organic synthesis. The main purpose as a sports nutrition beverage
ingredients
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Skype: yczht123456
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- Country: China (Mainland)
- Business Type:
- Market:No.388 Huangshan Road, Tianyuan District, Zhuzhou City, Hunan Province,China
- Founded Year:2013
- Address:No.388 Huangshan Road, Tianyuan District, Zhuzhou City, Hunan Province,China
- Contact:Mr John
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Chemical Name: 2-Ketoglutaric acid Alternate names: alpha-Ketoglutaric acid, a-Ketoglutaric acid, alpha Ketoglutarate, 2-Oxoglutaric acid, 2-Oxopentanedioic acid; AKG CAS: 328-50-7 EC Number: 206-330-3 INCI Name: Ketoglutaric acid Mol Formula: C5H6O5 Mol Weight: 146.10 Packaging ...
2-Ketoglutaric acid
Synonyms: 2-KETOGLUTARIC ACID;2-OXOGLUTARIC ACID;2-OXOPENTANEDIOIC ACID;A-KETOGLUTARIC ACID;ALPHA-KETOGLUTARIC ACID;GAMMA-KETOGLUTARIC ACID;FEMA 3891;KETO-GLU Product Details: Place of Origin: China Certification: ISO9001 Brand:YuanCheng Payment & Shipping Terms: Minimum Order ...
