Neomycin sulfate
English: Neomycin sulfate
CAS number: 1405-10-3
Molecular formula: C23H48N6O17S
Molecular weight: 712.7222
The content of 650 valence
15 / one billion cardboard packaging
Quality standard: the national standard
Appearance: white or yellowish powder, feed grade neomycin sulfate brown or brown powder, heat resistance, moisture absorption, easily soluble in water, slightly soluble in alcohol.
Pharmacological effects: the product by acting on the bacterial cell membrane associated ribosomes which interfere with bacterial protein synthesis, only short time contact with bacteria can kill
them. After oral administration in vivo gastrointestinal absorption range, mainly distributed in the extracellular fluid, and plasma protein binding rate is low (less than 20%), in vivo metabolism,
excretion to prototype. Therefore the body no residue, no toxicity to the animal, is safe for oral administration.
Use
1 this product belongs to the aminoglycoside antibiotic drugs containing 2- deoxystreptamine structure, can inhibit protein biosynthesis, so as to achieve the effect of inhibiting and killing
bacteria; this product in alkaline aqueous solution is a strong antibacterial effect. A potent bactericidal effect on Gram negative bacteria and some gram positive bacteria. Has inhibitory effect
on actinomyces, leptospirosis, amoeba.
2 commonly used in the treatment and control of neomycin sulfate sensitive bacteria (Escherichia coli, Shigella, Staphylococcus aureus, Salmonella, Arizona, proteus, Bacillus anthracis,
Streptococcus, Brucella Aerogenous etc.) infection caused by enteritis, dysentery, infectious rhinitis, respiratory infections and other diseases. There is also a certain effect of pneumococcus,
Pseudomonas aeruginosa, Pasteurella multocida and Mycobacterium tuberculosis.
Usage:
1 mixed drinks add: 35-70PPM, equivalent to 1000 liters of water to add this product 50~100 grams, connect to use 3~5 days.
2 mixing add: 70~140 PPM, equivalent to 1000KG of the full price of feed, add this product 100~200 grams, connect to use 3~5 days.
Two: according to the usage of livestock per kilogram of body weight of 15~25 mg / day, cent is taken two times, once every 3~5 days.
Usage three:
1 horses, cattle: 4~8 g / day; horse, calf: 2~3 g / day; piglets, lambs: 0.8~1 g / day; dogs: 0.2~0.5 g / day divided into two doses.
2 aerosol method to prevention and cure the chicken respiratory tract infection, dose of 1g/m3 house; or is equipped with 100 PPM sulfuric acid neomycin sprays, 2 times / day, droplet diameter
10~30 microns. Indoor residence time of 2 hours.
3 with 0.4 g of neomycin sulfate by adding sugar feeding bees, 1 times a day, QD for 5~7 days.
Combination therapy: clinical increased neomycin sulfate on Escherichia coli, Bacillus Proteus, brucellosis, viridans streptococci and enterococci infection effects, consider and tetracycline
(oxytetracycline, chlortetracycline, doxycycline, tetracycline hydrochloride etc), the large ring of lipids (kitasamycin, tilmicosin, erythromycin) or atropine combined use of drugs.
Storage: seal dry place.