Exenatide acetate
Product Name: Exenatide acetate
Synonyms: EXENATIDE ACETATE;ENFUVIRTIDE
ACETATE;Exenatide;His-Gly-Gly-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH{2};EXENATIDE
ACETATE(EXENDIN-4);Extendin-4;Unii-9p1872D4ol;His-Gly-Gly-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
CAS: 141732-76-5
MF: C186H284N50O62S
MW: 4244.60796
EINECS:
Product Categories: Peptide;Agonist;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals
Mol File: 141732-76-5.mol
Chemical Properties White Solid
Usage A 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 only in two positions close to the N-terminus.
Application of exenatide causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As
GLP-1, though with prolonged activity, exenatide augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide has found use as a medication of
diabetes II.
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