NVP-BKM120 Hydrochloride (Cas No. 1312445-63-8)
Product Quick Detail
- Cas No.
- 1312445-63-8
- Formula
- C18H22ClF3N6O2
- M.Wt
- 446.85
- Purity
- 98%
- Solubility
- DMSO ≥80mg/mL Water <1mg/mL Ethanol ≥20mg/mL
- Synonyms
- NVP-BKM120, Buparlisib
- Packaging
- Fluorinated Bottles
- Delivery
- 7 Days
Specifications
BKM120 is an orally bioavailable specific oral inhibitor of the pan-class I phosphatidylinositol 3 kinase (PI3K)
family of lipid kinases with potential antineoplastic activity. Buparlisib specifically inhibits class I PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway in an ATP-competitive
manner, thereby inhibiting the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate and activation of the PI3K signaling pathway.
- Country: China (Mainland)
- Market: European Union,Americas
- Founded Year: 2009
- Address: 武汉东湖高新区长城科技园光谷精工D栋402室
- Contact: Rosie Liu
