NVP-BKM120 Hydrochloride (Cas No. 1312445-63-8)

Product Quick Detail

Cas No.
1312445-63-8
Formula
C18H22ClF3N6O2
M.Wt
446.85
Purity
98%
Solubility
DMSO ≥80mg/mL Water <1mg/mL Ethanol ≥20mg/mL
Synonyms
NVP-BKM120, Buparlisib
Packaging
Fluorinated Bottles
Delivery
7 Days

BKM120 is an orally bioavailable specific oral inhibitor of the pan-class I phosphatidylinositol 3 kinase (PI3K) family of lipid kinases with potential antineoplastic activity. Buparlisib specifically inhibits class I PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway in an ATP-competitive manner, thereby inhibiting the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate and activation of the PI3K signaling pathway.
  • Country: China (Mainland)
  • Market: European Union,Americas
  • Founded Year: 2009
  • Address: 武汉东湖高新区长城科技园光谷精工D栋402室
  • Contact: Rosie Liu

Shanghai Sun-shine bio-technology Co., Ltd

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