MEK162 (Cas No. 606143-89-9)
Product Quick Detail
- Cas No.
- 606143-89-9
- M.Wt
- 441.23
- Solubility
- DMSO
- Formula
- C17H15BrF2N4O3
- Purity
- 98%
- Synonyms
- ARRY-438162; ARRY-162
- Packaging
- Fluorinated Bottles
- Delivery
- 7 Days
Specifications
ARRY-438162 (625 nM) inhibits in vitro osteoclast differentiation with IC50 of 39 nM. ARRY-438162 (10 μM) inhibits in vitro osteoclast resorption with IC50 of 625 nM. ARRY-438162 (2
μM) weakly affects osteoblast differentiation. ARRY-438162 is a recently disclosed potent and selective ATP non-competitive MEK1/2 inhibitor, inhibits pERK in cells with an
IC50 of11 nM. MEK162 (1 μM) combined with MK-2206 (2 μM) completely reverses the resistance of RSK-expressing MCF7
cells.
- Country: China (Mainland)
- Business Type:
- Market:European Union,Americas
- Founded Year:2009
- Address:武汉东湖高新区长城科技园光谷精工D栋402室
- Contact:Rosie Liu
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