Afatinib dimaleate (Cas No.850140-73-7)
Product Quick Detail
- Cas No.
- 850140-73-7
- M.Wt
- 718.08
- Solubility
- DMSO
- Formula
- C32H33ClFN5O11
- Purity
- 98%
- Synonyms
- BIBW 2992MA2; BIBW-2992; BIBW2992; BIBW 2992; Afatinib
- Packaging
- Fluorinated Bottles
- Delivery
- 7 Days
Specifications
Afatinib (BIBW2992) irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively; 100-fold
more active against Gefitinib-resistant L858R-T790M EGFR mutant.
- Country: China (Mainland)
- Business Type:
- Market:European Union,Americas
- Founded Year:2009
- Address:武汉东湖高新区长城科技园光谷精工D栋402室
- Contact:Rosie Liu
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Afatinib (BIBW2992) irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM in cell-free assays, respectively; 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant. ...
