PLX647 (Cas No. 873786-09-5)
Product Quick Detail
- Cas No.
- 873786-09-5
- Formula
- C21H17F3N4
- M.Wt
- 382.38
- Purity
- 98%
- Solubility
- DMSO 20 mg/ml
- Synonyms
- PLX-647
- Packaging
- Fluorinated Bottles
- Delivery
- 7 Days
Specifications
PLX647 was tested against a panel of 400 kinases at a concentration of 1 μM, 35-fold above its FMS enzymatic IC50 and 60-fold above its KIT enzymatic IC50. In addition to FMS and
KIT, the activities of only nine kinases were inhibited by more than 50%. PLX647 potently inhibits the growth of FLT3–ITD-expressing MV4-11 cells (IC50 = 0.11 μM) but not OCI-AML5 (IC50 = 1.6 μM),
which express wild-type FLT3.
- Country: China (Mainland)
- Business Type:
- Market:European Union,Americas
- Founded Year:2009
- Address:武汉东湖高新区长城科技园光谷精工D栋402室
- Contact:Rosie Liu
