Ispinesib (Cas No. 336113-53-2)

Product Quick Detail

Cas No.
336113-53-2
Formula
C30H33ClN4O2
M.Wt
517.06
Purity
98%
Solubility
DMSO 100 mg/mL Ethanol 100 mg/mL
Synonyms
SB-715992; SB 715992; SB715992
Packaging
Fluorinated Bottles
Delivery
7 Days

Ispinesib is a potent, allosteric, reversible, and specific inhibitor of KSP, which changes the binding property of KSP to microtubules and disturbs its movement by inhibiting ADP release without altering the release of the KSP-ADP complex from the microtubule. Ispinesib shows potent cytotoxic activity in a panel of tumor cell lines, including Colo205, Colo201, HT-29, M5076, Madison-109, and MX-1, with IC50 of 1.2 nM to 9.5 nM.
  • Country: China (Mainland)
  • Business Type:
  • Market:European Union,Americas
  • Founded Year:2009
  • Address:武汉东湖高新区长城科技园光谷精工D栋402室
  • Contact:Rosie Liu
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