Ispinesib (Cas No. 336113-53-2)
Product Quick Detail
- Cas No.
- 336113-53-2
- M.Wt
- 517.06
- Solubility
- DMSO 100 mg/mL Ethanol 100 mg/mL
- Formula
- C30H33ClN4O2
- Purity
- 98%
- Synonyms
- SB-715992; SB 715992; SB715992
- Packaging
- Fluorinated Bottles
- Delivery
- 7 Days
Specifications
Ispinesib is a potent, allosteric, reversible, and specific inhibitor of KSP, which changes the binding property of KSP to microtubules and disturbs its movement by inhibiting ADP
release without altering the release of the KSP-ADP complex from the microtubule. Ispinesib shows potent cytotoxic activity in a panel of tumor cell lines, including Colo205, Colo201, HT-29, M5076,
Madison-109, and MX-1, with IC50 of 1.2 nM to 9.5 nM.
- Country: China (Mainland)
- Business Type:
- Market:European Union,Americas
- Founded Year:2009
- Address:武汉东湖高新区长城科技园光谷精工D栋402室
- Contact:Rosie Liu
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