RKI-1447 (Cas No. 1342278-01-6)

Product Quick Detail

Cas No.
1342278-01-6
Formula
C16H14N4O2S
M.Wt
326.37
Purity
98%
Solubility
DMSO
Synonyms
RKI 1447; RKI1447
Packaging
Fluorinated Bottles
Delivery
7 Days

RKI-1447 inhibits potently ROCK1 and ROCK2 in a dose-dependent manner with IC50 values of 14.5 nM and 6.2 nM, respectively. RKI-1447 suppressed phosphorylation of the ROCK substrates MLC-2 and MYPT-1 in human cancer cells, but had no effect on the phosphorylation levels of the AKT, MEK, and S6 kinase at concentrations as high as 10 μmol/L.
  • Country: China (Mainland)
  • Market: European Union,Americas
  • Founded Year: 2009
  • Address: 武汉东湖高新区长城科技园光谷精工D栋402室
  • Contact: Rosie Liu

Shanghai Sun-shine bio-technology Co., Ltd

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