JSH-23 (Cas No.749886-87-1)
Product Quick Detail
- Cas No.
- 749886-87-1
- Formula
- C16H20N2
- M.Wt
- 240.34
- Purity
- 98%
- Solubility
- DMSO 48 mg/mL; Water <1 mg/mL
- Synonyms
- JSH 23; JSH23
- Packaging
- Fluorinated Bottles
- Delivery
- 7 Days
Specifications
JSH-23 exhibited inhibitory effect with an IC(50) value of 7.1 microM on nuclear factor (NF)-kappaB transcriptional activity in lipopolysaccharide (LPS)-stimulated macrophages RAW
264.7, and interfered LPS-induced nuclear translocation of NF-kappaB without affecting IkappaB degradation. JSH-23 inhibits LPS-induced nuclear translocation of NF-κB p65 without affecting IκBα
degradation. JSH-23 inhibits LPS-induced apoptotic chromatin condensation, while does not show significant cytotoxic effects on the RAW 264.7 cells at <100 μM.
- Country: China (Mainland)
- Business Type:
- Market:European Union,Americas
- Founded Year:2009
- Address:武汉东湖高新区长城科技园光谷精工D栋402室
- Contact:Rosie Liu
