Tacrolimus CAS:104987-11-3
MF: C44H69NO12
MW: 804.02
Product Categories: Active Pharmaceutical Ingredients;Immunosuppressant.;Intermediates & Fine Chemicals;Pharmaceuticals;API;Chiral Reagents;Fujimycin, Prograf;antibiotic
Mol File: 104987-11-3.mol
Chemical Properties
Appreance : White Crystalline Solid
mp : 113-115°C
storage temp. : 20°C
solubility DMSO: >3 mg/mL
form : solid
color : white
CAS DataBase Reference: 104987-11-3(CAS DataBase Reference)
Usage: An immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein,
thereby reversing its effects on sarcoplasmic reticulum Ca+2 release.
Usage: FK-506 (Tacrolimus) is a macrolide immunosuppressive drug that is mainly used after allogeneic organ transplant to reduce the activity of the patient's immune system
Usage: Tacrolimus (fujimycin) was discovered as a potent inhibitor of IL2 production in a targeted search for novel immunosuppressants. Tacrolimus acts by blocking T cell proliferation in vitro by
inhibiting the generation of several lymphokines, notably the original target IL-2. Tacrolimus inhibits the activity of FK-506 binding protein, Ca2+-dependent phosphatase and calcineurin, and
activates NF-κB through phosphorylation and degradation of IκBα.
Usage: treatment of Cushing's syndrome
Usage: For use after allogenic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It was first approved by the FDA in 1994 for use in liver
transplantation, this has been extended to include kidney, heart,
----------Additional Information ------------
Place of origin : China
Brand : YC
Certificate : ISO9001, KOSHER, GMP, SGS
Minimum order quantity : 5 Grams
Production capacity : 1000 Kilograms/Month
-----------Delivery Information -------------
Packing : Foil bag/tin or as your request
Payment : T/T, Western Union, MoneyGram
Port : Shanghai, Shenzhen, Hongkong
Shipment method : EMS, DHL, FeDex, UPS, etc
Leading time : Within 24 hours after payment
Delivery time : safe & timely, around 4 days after payment.
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