Trilostane CAS: 13647-35-3
Product Quick Detail
- Place Of Origin
- China
- Minimum Order
- 1
- Packaging
- as your request
- Delivery
- 10 Days
Specifications
Trilostane CAS: 13647-35-3
MF: C20H27NO3
MW: 329.43
EINECS: 237-133-0
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Inhibitor;FULVICIN
Mol File: 13647-35-3.mol
Chemical Properties
Appearance: White to pale white solid
mp : 264 °C
storage temp. : -20°C Freezer
CAS DataBase Reference: 13647-35-3(CAS DataBase Reference)
EPA Substance Registry System: Androst-2-ene-2- carbonitrile, 4,5-epoxy-3,17-dihydroxy-, (4.alpha.,5.alpha.,17.beta.)- (13647-35-3)
Melting point: 257°C to 270°C
Loss on drying: ≤0.5%
Optical rotation: negative 0.10° to +0.10°determined on solution S.
Solubility: Freely soluble in water,practically insoluble or very slightly soluble in alcohol and in methylene chloride.
Appearance of solution: Solution S is clear and not more intensely coloured than reference solution in BY6.
Usage :
Trilostane can inhibit cortical hormone in the process of synthesis of 3 beta dehydrogenase, make the cortisol, aldosterone synthesis decreased, clinically used in the treatment of Cushing syndrome
(hypercortisolism) and primary aldosteronism. This product also had significantly effect to decreased serum testosterone level.
Application:
Trilostane is used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.
Trilostane blocks an enzyme involved in the production of several steroide including cortisol. Inhibiting this enzyme inhibits the production of cortisol. In Cushing's syndrome, the adrenal gland
overproduces steroide. Although steroide are important for various functions of the body, too much can cause problems. Trilostane reduces the amount of steroide produced by the adrenal gland.
Trilostane produces suppression of the adrenal cortex by inhibiting enzymatic conversion of steroide by 3-beta-hydroxysteroie dehydrogenase/delta 5,4 ketosteroide isomerase, thus blocking synthesis
of adrenal steroide.
Side effect:
Symptoms of overdose include darkening of skin, drowsiness or tiredness, loss of appetite, mental depression, skin rash, and/or vomiting.
----------Additional Information ------------
Place of origin : China
Brand : YC
Certificate : ISO9001, KOSHER, GMP, SGS
Minimum order quantity : 5 Grams
Production capacity : 1000 Kilograms/Month
-----------Delivery Information -------------
Packing : Foil bag/tin or as your request
Payment : T/T, Western Union, MoneyGram
Port : Shanghai, Shenzhen, Hongkong
Shipment method : EMS, DHL, FeDex, UPS, etc
Leading time : Within 24 hours after payment
Delivery time : safe & timely, around 4 days after payment.
----------Our Competitive Advantages -----------
1,Rich experience.
Our company is a professional production leading factory in China in pharmaceutical area of many years
2,Great quality, purity and favourable.
Our company is a professional leading factory in China in pharmaceutical area.Good quality is one of our secret success.
3,Safe and fast delivery.
We have stock, so we can delivery quickly at the very day when receive the payment.
4,Package: Professional packing with professional materials
5,Competitive Prices : Low price with high qulity
6,Good after-sales service : making all efforts to meet customers' need.
- Country: China (Mainland)
- Business Type: Manufacturer
- Market:European Union
- Founded Year:20098
- Address:No. 496 Zhongshan Road, Wuchang, Wuhan, Hubei
- Contact:Cheryl Zhao
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